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Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis

BACKGROUND: Prostate cancer (PCa) cells preferentially metastasize to bone at least in part by acquiring osteomimetic properties. Runx2, an osteoblast master transcription factor, is aberrantly expressed in PCa cells, and promotes their metastatic phenotype. The transcriptional programs regulated by...

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Detalles Bibliográficos
Autores principales: Baniwal, Sanjeev K, Khalid, Omar, Gabet, Yankel, Shah, Ruchir R, Purcell, Daniel J, Mav, Deepak, Kohn-Gabet, Alice E, Shi, Yunfan, Coetzee, Gerhard A, Frenkel, Baruch
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955618/
https://www.ncbi.nlm.nih.gov/pubmed/20863401
http://dx.doi.org/10.1186/1476-4598-9-258