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Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis
BACKGROUND: Prostate cancer (PCa) cells preferentially metastasize to bone at least in part by acquiring osteomimetic properties. Runx2, an osteoblast master transcription factor, is aberrantly expressed in PCa cells, and promotes their metastatic phenotype. The transcriptional programs regulated by...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955618/ https://www.ncbi.nlm.nih.gov/pubmed/20863401 http://dx.doi.org/10.1186/1476-4598-9-258 |