Down-regulation of the Nucleotide Excision Repair gene XPG as a new mechanism of drug resistance in human and murine cancer cells

BACKGROUND: Drug resistance is one of the major obstacles limiting the activity of anticancer agents. Activation of DNA repair mechanism often accounts for increase resistance to cancer chemotherapy. RESULTS: We present evidence that nemorubicin, a doxorubicin derivative currently in clinical evalua...

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Detalles Bibliográficos
Autores principales: Sabatino, Maria Antonietta, Marabese, Mirko, Ganzinelli, Monica, Caiola, Elisa, Geroni, Cristina, Broggini, Massimo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955619/
https://www.ncbi.nlm.nih.gov/pubmed/20868484
http://dx.doi.org/10.1186/1476-4598-9-259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955619/
https://www.ncbi.nlm.nih.gov/pubmed/20868484
http://dx.doi.org/10.1186/1476-4598-9-259

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