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Cytotoxic T cells expressing the co-stimulatory receptor NKG2 D are increased in cigarette smoking and COPD

BACKGROUND: A suggested role for T cells in COPD pathogenesis is based on associations between increased lung cytotoxic T lymphocyte (CD8(+)) numbers and airflow limitation. CD69 is an early T cell activation marker. Natural Killer cell group 2 D (NKG2D) receptors are co-stimulatory molecules induce...

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Detalles Bibliográficos
Autores principales: Roos-Engstrand, Ester, Pourazar, Jamshid, Behndig, Annelie F, Blomberg, Anders, Bucht, Anders
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955660/
https://www.ncbi.nlm.nih.gov/pubmed/20863413
http://dx.doi.org/10.1186/1465-9921-11-128