Human Artificial Chromosome with a Conditional Centromere for Gene Delivery and Gene Expression

Human artificial chromosomes (HACs), which carry a fully functional centromere and are maintained as a single-copy episome, are not associated with random mutagenesis and offer greater control over expression of ectopic genes on the HAC. Recently, we generated a HAC with a conditional centromere, wh...

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Detalles Bibliográficos
Autores principales: Iida, Yuichi, Kim, Jung-Hyun, Kazuki, Yasuhiro, Hoshiya, Hidetoshi, Takiguchi, Masato, Hayashi, Masahiro, Erliandri, Indri, Lee, Hee-Sheung, Samoshkin, Alex, Masumoto, Hiroshi, Earnshaw, William C., Kouprina, Natalay, Larionov, Vladimir, Oshimura, Mitsuo
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955713/
https://www.ncbi.nlm.nih.gov/pubmed/20798231
http://dx.doi.org/10.1093/dnares/dsq020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955713/
https://www.ncbi.nlm.nih.gov/pubmed/20798231
http://dx.doi.org/10.1093/dnares/dsq020

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