Targeting poly(ADP-ribose) polymerase activity for cancer therapy

Poly(ADP-ribosyl)ation is a ubiquitous protein modification found in mammalian cells that modulates many cellular responses, including DNA repair. The poly(ADP-ribose) polymerase (PARP) family catalyze the formation and addition onto proteins of negatively charged ADP-ribose polymers synthesized fro...

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Detalles Bibliográficos
Autores principales: Mégnin-Chanet, Frédérique, Bollet, Marc A., Hall, Janet
Formato: Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2010
Materias:
Multi-Author Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955921/
https://www.ncbi.nlm.nih.gov/pubmed/20725763
http://dx.doi.org/10.1007/s00018-010-0490-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955921/
https://www.ncbi.nlm.nih.gov/pubmed/20725763
http://dx.doi.org/10.1007/s00018-010-0490-8

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