P-Glycoprotein/MDR1 Regulates Pokemon Gene Transcription Through p53 Expression in Human Breast Cancer Cells

P-glycoprotein (Pgp), encoded by the multidrug resistance 1 (MDR1) gene, is an efflux transporter and plays an important role in pharmacokinetics. In this study, we demonstrated that the pokemon promoter activity, the pokemon mRNA and protein expression can be significantly inhibited by Pgp. Chromat...

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Detalles Bibliográficos
Autores principales: He, Shengnan, Liu, Feng, Xie, Zhenhua, Zu, Xuyu, Xu, Wei, Jiang, Yuyang
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956079/
https://www.ncbi.nlm.nih.gov/pubmed/20957096
http://dx.doi.org/10.3390/ijms11093039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956079/
https://www.ncbi.nlm.nih.gov/pubmed/20957096
http://dx.doi.org/10.3390/ijms11093039

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