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En route to photoaffinity labeling of the bacterial lectin FimH

Mannose-specific adhesion of Escherichia coli bacteria to cell surfaces, the cause of various infections, is mediated by a fimbrial lectin, called FimH. X-ray studies have revealed a carbohydrate recognition domain (CRD) on FimH that can complex α-D-mannosides. However, as the precise nature of the...

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Detalles Bibliográficos
Autores principales: Lindhorst, Thisbe K, Märten, Michaela, Fuchs, Andreas, Knight, Stefan D
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956469/
https://www.ncbi.nlm.nih.gov/pubmed/20978617
http://dx.doi.org/10.3762/bjoc.6.91