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Inhibition of Cellular Protein Secretion by Norwalk Virus Nonstructural Protein p22 Requires a Mimic of an Endoplasmic Reticulum Export Signal

Protein trafficking between the endoplasmic reticulum (ER) and Golgi apparatus is central to cellular homeostasis. ER export signals are utilized by a subset of proteins to rapidly exit the ER by direct uptake into COPII vesicles for transport to the Golgi. Norwalk virus nonstructural protein p22 co...

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Detalles Bibliográficos
Autores principales: Sharp, Tyler M., Guix, Susana, Katayama, Kazuhiko, Crawford, Sue E., Estes, Mary K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956632/
https://www.ncbi.nlm.nih.gov/pubmed/20976190
http://dx.doi.org/10.1371/journal.pone.0013130