Mitochondrial Uncoupling Inhibits p53 Mitochondrial Translocation in TPA-Challenged Skin Epidermal JB6 Cells

The tumor suppressor p53 is known to be able to trigger apoptosis in response to DNA damage, oncogene activation, and certain chemotherapeutic drugs. In addition to its transcriptional activation, a fraction of p53 translocates to mitochondria at the very early stage of apoptosis, which eventually c...

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Detalles Bibliográficos
Autores principales: Wang, Fei, Fu, Xueqi, Chen, Xia, Chen, Xinbin, Zhao, Yunfeng
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956637/
https://www.ncbi.nlm.nih.gov/pubmed/20976134
http://dx.doi.org/10.1371/journal.pone.0013459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956637/
https://www.ncbi.nlm.nih.gov/pubmed/20976134
http://dx.doi.org/10.1371/journal.pone.0013459

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