Mitochondrial DNA Sequence Variation and Haplogroup Distribution in Chinese Patients with LHON and m.14484T>C

BACKGROUND: Leber hereditary optic neuropathy (LHON, MIM 535000) is one of the most common mitochondrial genetic disorders caused by three primary mtDNA mutations (m.3460G>A, m.11778G>A and m. 14484T>C). The clinical expression of LHON is affected by many additional factors, e.g. mtDNA back...

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Detalles Bibliográficos
Autores principales: Yu, Dandan, Jia, Xiaoyun, Zhang, A-Mei, Li, Shiqiang, Zou, Yang, Zhang, Qingjiong, Yao, Yong-Gang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956641/
https://www.ncbi.nlm.nih.gov/pubmed/20976138
http://dx.doi.org/10.1371/journal.pone.0013426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956641/
https://www.ncbi.nlm.nih.gov/pubmed/20976138
http://dx.doi.org/10.1371/journal.pone.0013426

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