Highly Efficient Elimination of Colorectal Tumor-Initiating Cells by an EpCAM/CD3-Bispecific Antibody Engaging Human T Cells

With their resistance to genotoxic and anti-proliferative drugs and potential to grow tumors and metastases from very few cells, cancer stem or tumor-initiating cells (TICs) are a severe limitation for the treatment of cancer by conventional therapies. Here, we explored whether human T cells that ar...

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Detalles Bibliográficos
Autores principales: Herrmann, Ines, Baeuerle, Patrick A., Friedrich, Matthias, Murr, Alexander, Filusch, Susanne, Rüttinger, Dominik, Majdoub, Mariam W., Sharma, Sherven, Kufer, Peter, Raum, Tobias, Münz, Markus
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956687/
https://www.ncbi.nlm.nih.gov/pubmed/20976159
http://dx.doi.org/10.1371/journal.pone.0013474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956687/
https://www.ncbi.nlm.nih.gov/pubmed/20976159
http://dx.doi.org/10.1371/journal.pone.0013474

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