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Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathy

BACKGROUND: We investigated whether early combined autologous adipose-derived mesenchymal stem cell (ADMSC) and sildenafil therapy offers an additive benefit in preserving heart function in rat dilated cardiomyopathy (DCM). METHODS: Adult Lewis rats (n = 8 per group) were divided into group 1 (norma...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Chun, Leu, Steve, Sun, Cheuk-Kwan, Yen, Chia-Hung, Kao, Ying-Hsien, Chang, Li-Teh, Tsai, Tzu-Hsien, Chua, Sarah, Fu, Morgan, Ko, Sheung-Fat, Wu, Chiung-Jen, Lee, Fan-Yen, Yip, Hon-Kan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956711/
https://www.ncbi.nlm.nih.gov/pubmed/20868517
http://dx.doi.org/10.1186/1479-5876-8-88