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Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection

BACKGROUND: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the emergence of resistant strains. The outlook is worsened by the absence of promising drug targets for this disease. We have...

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Detalles Bibliográficos
Autores principales: Flórez, Andrés F, Park, Daeui, Bhak, Jong, Kim, Byoung-Chul, Kuchinsky, Allan, Morris, John H, Espinosa, Jairo, Muskus, Carlos
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956735/
https://www.ncbi.nlm.nih.gov/pubmed/20875130
http://dx.doi.org/10.1186/1471-2105-11-484