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Inferring PDZ Domain Multi-Mutant Binding Preferences from Single-Mutant Data

Many important cellular protein interactions are mediated by peptide recognition domains. The ability to predict a domain's binding specificity directly from its primary sequence is essential to understanding the complexity of protein-protein interaction networks. One such recognition domain is...

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Detalles Bibliográficos
Autores principales: Zaslavsky, Elena, Bradley, Philip, Yanover, Chen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956758/
https://www.ncbi.nlm.nih.gov/pubmed/20976110
http://dx.doi.org/10.1371/journal.pone.0012787