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Autocrine Interferon Priming in Macrophages but Not Dendritic Cells Results in Enhanced Cytokine and Chemokine Production after Coronavirus Infection

Coronaviruses efficiently inhibit interferon (IFN) induction in nonhematopoietic cells and conventional dendritic cells (cDC). However, IFN is produced in infected macrophages, microglia, and plasmacytoid dendritic cells (pDC). To begin to understand why IFN is produced in infected macrophages, we i...

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Detalles Bibliográficos
Autores principales: Zhou, Haixia, Zhao, Jincun, Perlman, Stanley
Formato: Texto
Lenguaje:English
Publicado: American Society of Microbiology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957079/
https://www.ncbi.nlm.nih.gov/pubmed/20978536
http://dx.doi.org/10.1128/mBio.00219-10