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Autocrine Interferon Priming in Macrophages but Not Dendritic Cells Results in Enhanced Cytokine and Chemokine Production after Coronavirus Infection
Coronaviruses efficiently inhibit interferon (IFN) induction in nonhematopoietic cells and conventional dendritic cells (cDC). However, IFN is produced in infected macrophages, microglia, and plasmacytoid dendritic cells (pDC). To begin to understand why IFN is produced in infected macrophages, we i...
Autores principales: | Zhou, Haixia, Zhao, Jincun, Perlman, Stanley |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957079/ https://www.ncbi.nlm.nih.gov/pubmed/20978536 http://dx.doi.org/10.1128/mBio.00219-10 |
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