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BRAF p.Val600Glu (V600E) Testing for Assessment of Treatment Options in Metastatic Colorectal Cancer

Colon and rectal cancer (CRC) are the third most common cancer in the United States and cause approximately 50,000 deaths per year. The anti–epidermal growth factor receptor (EGFR) monoclonal antibodies cetuximab (Erbitux®) and panitumumab (Vectibix®) have been recently introduced to treat CRC. Howe...

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Detalles Bibliográficos
Autores principales: Lea, Andrew, Allingham-Hawkins, Diane, Levine, Susan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957244/
https://www.ncbi.nlm.nih.gov/pubmed/20972475
http://dx.doi.org/10.1371/currents.RRN1187