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Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines

The tumor suppressor gene PTEN (phosphatase and tensin homolog deleted on chromosome 10) and the androgen receptor (AR) play important roles in tumor development and progression in prostate carcinogenesis. Among many functions, PTEN negatively regulates the cytoplasmic phosphatidylinositol-3-kinase/...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Romigh, Todd, He, Xin, Orloff, Mohammed S., Silverman, Robert H., Heston, Warren D., Eng, Charis
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957324/
https://www.ncbi.nlm.nih.gov/pubmed/20729295
http://dx.doi.org/10.1093/hmg/ddq354