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Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines
The tumor suppressor gene PTEN (phosphatase and tensin homolog deleted on chromosome 10) and the androgen receptor (AR) play important roles in tumor development and progression in prostate carcinogenesis. Among many functions, PTEN negatively regulates the cytoplasmic phosphatidylinositol-3-kinase/...
Autores principales: | Wang, Yu, Romigh, Todd, He, Xin, Orloff, Mohammed S., Silverman, Robert H., Heston, Warren D., Eng, Charis |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957324/ https://www.ncbi.nlm.nih.gov/pubmed/20729295 http://dx.doi.org/10.1093/hmg/ddq354 |
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