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RNA Interference in Schistosoma mansoni Schistosomula: Selectivity, Sensitivity and Operation for Larger-Scale Screening

BACKGROUND: The possible emergence of resistance to the only available drug for schistosomiasis spurs drug discovery that has been recently incentivized by the availability of improved transcriptome and genome sequence information. Transient RNAi has emerged as a straightforward and important techni...

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Detalles Bibliográficos
Autores principales: Štefanić, Saša, Dvořák, Jan, Horn, Martin, Braschi, Simon, Sojka, Daniel, Ruelas, Debbie S., Suzuki, Brian, Lim, Kee-Chong, Hopkins, Stephanie D., McKerrow, James H., Caffrey, Conor R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957409/
https://www.ncbi.nlm.nih.gov/pubmed/20976050
http://dx.doi.org/10.1371/journal.pntd.0000850