Cargando…

The NKG2D Ligands RAE-1δ and RAE-1ε Differ with Respect to Their Receptor Affinity, Expression Profiles and Transcriptional Regulation

BACKGROUND: RAE-1 is a ligand of the activating receptor NKG2D expressed by NK cells, NKT, γδT and some CD8(+)T lymphocytes. RAE-1 is overexpressed in tumor cell lines and its expression is induced after viral infection and genotoxic stress. We have recently demonstrated that RAE-1 is expressed in t...

Descripción completa

Detalles Bibliográficos
Autores principales: Cédile, Oriane, Popa, Natalia, Pollet-Villard, Frédéric, Garmy, Nicolas, Ibrahim, El Chérif, Boucraut, José
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957426/
https://www.ncbi.nlm.nih.gov/pubmed/20976056
http://dx.doi.org/10.1371/journal.pone.0013466