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Tn-seq; high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms
Biological pathways are structured in complex networks of interacting genes. Solving the architecture of such networks may provide valuable information, such as how microorganisms cause disease. Here we present a method (Tn-seq) for accurately determining quantitative genetic interactions on a genom...
Autores principales: | van Opijnen, Tim, Bodi, Kip L., Camilli, Andrew |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957483/ https://www.ncbi.nlm.nih.gov/pubmed/19767758 http://dx.doi.org/10.1038/nmeth.1377 |
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