Proteasome inhibitor-induced apoptosis is mediated by positive feedback amplification of PKCδ proteolytic activation and mitochondrial translocation

Emerging evidence implicates impaired protein degradation by the ubiquitin proteasome system (UPS) in Parkinson's disease; however cellular mechanisms underlying dopaminergic degeneration during proteasomal dysfunction are yet to be characterized. In the present study, we identified that the no...

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Detalles Bibliográficos
Autores principales: Sun, Faneng, Kanthasamy, Arthi, Song, Chunjuan, Yang, Yongjie, Anantharam, Vellareddy, Kanthasamy, Anumantha G
Formato: Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957660/
https://www.ncbi.nlm.nih.gov/pubmed/18298651
http://dx.doi.org/10.1111/j.1582-4934.2008.00293.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957660/
https://www.ncbi.nlm.nih.gov/pubmed/18298651
http://dx.doi.org/10.1111/j.1582-4934.2008.00293.x

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