IKKβ inhibitor identification: a multi-filter driven novel scaffold

BACKGROUND: Nuclear factor kappa B (NF-κB) is a chief nuclear transcription factor that controls the transcription of various genes; and its activation is tightly controlled by Inhibitor kappa B kinase (IKK). The irregular transcription of NF-κB has been linked to auto-immune disorders, cancer and o...

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Detalles Bibliográficos
Autores principales: Nagarajan, Shanthi, Choo, Hyunah, Cho, Yong Seo, Shin, Kye Jung, Oh, Kwang-Seok, Lee, Byung Ho, Pae, Ae Nim
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957683/
https://www.ncbi.nlm.nih.gov/pubmed/21106122
http://dx.doi.org/10.1186/1471-2105-11-S7-S15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957683/
https://www.ncbi.nlm.nih.gov/pubmed/21106122
http://dx.doi.org/10.1186/1471-2105-11-S7-S15

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