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IKKβ inhibitor identification: a multi-filter driven novel scaffold
BACKGROUND: Nuclear factor kappa B (NF-κB) is a chief nuclear transcription factor that controls the transcription of various genes; and its activation is tightly controlled by Inhibitor kappa B kinase (IKK). The irregular transcription of NF-κB has been linked to auto-immune disorders, cancer and o...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957683/ https://www.ncbi.nlm.nih.gov/pubmed/21106122 http://dx.doi.org/10.1186/1471-2105-11-S7-S15 |