Synthesis and biological activity of α-l-fucosyl ceramides, analogues of the potent agonist, α-d-galactosyl ceramide KRN7000

Several l-fucoglycolipids are associated with diseases such as cancer, cystic fibrosis and rheumatoid arthritis. Activation of iNKT cells is known to lead to the production of cytokines that can help alleviate or exacerbate these conditions. α-Galactosyl ceramide (α-GalCer) is a known agonist of iNK...

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Detalles Bibliográficos
Autores principales: Veerapen, Natacha, Reddington, Faye, Bricard, Gabriel, Porcelli, Steven A., Besra, Gurdyal S.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957807/
https://www.ncbi.nlm.nih.gov/pubmed/20462758
http://dx.doi.org/10.1016/j.bmcl.2010.04.079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957807/
https://www.ncbi.nlm.nih.gov/pubmed/20462758
http://dx.doi.org/10.1016/j.bmcl.2010.04.079

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