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Targeting the Vasoprotective Axis of the Renin-Angiotensin System: A Novel Strategic Approach to Pulmonary Hypertensive Therapy

A decade has passed since the discovery of angiotensin-converting enzyme 2 (ACE2), a component of the ACE2–angiotensin (Ang)-(1-7)–Mas counterregulatory axis of the renin angiotensin system (RAS). ACE2 is considered an endogenous regulator of the vasoconstrictive, proliferative, fibrotic, and proinf...

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Detalles Bibliográficos
Autores principales: Bradford, Chastity N., Ely, Debra R., Raizada, Mohan K.
Formato: Texto
Lenguaje:English
Publicado: Current Science Inc. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957877/
https://www.ncbi.nlm.nih.gov/pubmed/20556668
http://dx.doi.org/10.1007/s11906-010-0122-6