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Regulation of Pathologic Retinal Angiogenesis in Mice and Inhibition of VEGF-VEGFR2 Binding by Soluble Heparan Sulfate

Development of the retinal vascular network is strictly confined within the neuronal retina, allowing the intraocular media to be optically transparent. However, in retinal ischemia, pro-angiogenic factors (including vascular endothelial growth factor-A, VEGF-A) induce aberrant guidance of retinal v...

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Detalles Bibliográficos
Autores principales: Nishiguchi, Koji M., Kataoka, Keiko, Kachi, Shu, Komeima, Keiichi, Terasaki, Hiroko
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958111/
https://www.ncbi.nlm.nih.gov/pubmed/20975989
http://dx.doi.org/10.1371/journal.pone.0013493