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A Functional Polymorphism in Renalase (Glu37Asp) Is Associated with Cardiac Hypertrophy, Dysfunction, and Ischemia: Data from the Heart and Soul Study

BACKGROUND: Renalase is a soluble enzyme that metabolizes circulating catecholamines. A common missense polymorphism in the flavin-adenine dinucleotide-binding domain of human renalase (Glu37Asp) has recently been described. The association of this polymorphism with cardiac structure, function, and...

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Detalles Bibliográficos
Autores principales: Farzaneh-Far, Ramin, Desir, Gary V., Na, Beeya, Schiller, Nelson B., Whooley, Mary A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958117/
https://www.ncbi.nlm.nih.gov/pubmed/20975995
http://dx.doi.org/10.1371/journal.pone.0013496