ADAM17 Deletion in Thymic Epithelial Cells Alters Aire Expression without Affecting T Cell Developmental Progression

BACKGROUND: Cellular interactions between thymocytes and thymic stromal cells are critical for normal T cell development. Thymic epithelial cells (TECs) are important stromal niche cells that provide essential growth factors, cytokines, and present self-antigens to developing thymocytes. The identif...

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Detalles Bibliográficos
Autores principales: Gravano, David M., McLelland, Bryce T., Horiuchi, Keisuke, Manilay, Jennifer O.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958126/
https://www.ncbi.nlm.nih.gov/pubmed/20976004
http://dx.doi.org/10.1371/journal.pone.0013528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958126/
https://www.ncbi.nlm.nih.gov/pubmed/20976004
http://dx.doi.org/10.1371/journal.pone.0013528

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