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Intertwining Threshold Settings, Biological Data and Database Knowledge to Optimize the Selection of Differentially Expressed Genes from Microarray

BACKGROUND: Many tools used to analyze microarrays in different conditions have been described. However, the integration of deregulated genes within coherent metabolic pathways is lacking. Currently no objective selection criterion based on biological functions exists to determine a threshold demons...

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Detalles Bibliográficos
Autores principales: Chuchana, Paul, Holzmuller, Philippe, Vezilier, Frederic, Berthier, David, Chantal, Isabelle, Severac, Dany, Lemesre, Jean Loup, Cuny, Gerard, Nirdé, Philippe, Bucheton, Bruno
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958130/
https://www.ncbi.nlm.nih.gov/pubmed/20976008
http://dx.doi.org/10.1371/journal.pone.0013518