S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and regulatory T cells

Naïve CD4(+) T cells differentiate into diverse effector and regulatory lineages to orchestrate immunity and tolerance. The differentiation of pro-inflammatory T(H)1 and anti-inflammatory Foxp3+ regulatory T cells (Treg) was reciprocally regulated by S1P(1), a receptor for the bioactive lipid sphing...

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Detalles Bibliográficos
Autores principales: Liu, Guangwei, Yang, Kai, Burns, Samir, Shrestha, Sharad, Chi, Hongbo
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958252/
https://www.ncbi.nlm.nih.gov/pubmed/20852647
http://dx.doi.org/10.1038/ni.1939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958252/
https://www.ncbi.nlm.nih.gov/pubmed/20852647
http://dx.doi.org/10.1038/ni.1939

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