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Myocardial stress remodelling after regional infarction is independent of glycogen synthase kinase-3 inactivation

Phosphorylation and inactivation of glycogen synthase kinase 3 (GSK-3) is observed in the failing heart induced by chronic pharmacological stress and aortic banding. Constitutive kinase activity attenuates pathological remodelling, suggesting an obligatory role in stress signalling. However, this ha...

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Detalles Bibliográficos
Autores principales: Webb, Ian G., Sicard, Pierre, Clark, James E, Redwood, Simon, Marber, Michael S.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958307/
https://www.ncbi.nlm.nih.gov/pubmed/20696171
http://dx.doi.org/10.1016/j.yjmcc.2010.07.021