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Myocardial stress remodelling after regional infarction is independent of glycogen synthase kinase-3 inactivation
Phosphorylation and inactivation of glycogen synthase kinase 3 (GSK-3) is observed in the failing heart induced by chronic pharmacological stress and aortic banding. Constitutive kinase activity attenuates pathological remodelling, suggesting an obligatory role in stress signalling. However, this ha...
Autores principales: | Webb, Ian G., Sicard, Pierre, Clark, James E, Redwood, Simon, Marber, Michael S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958307/ https://www.ncbi.nlm.nih.gov/pubmed/20696171 http://dx.doi.org/10.1016/j.yjmcc.2010.07.021 |
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