Activation of the cardiac Na(+)–Ca(2+) exchanger by sorcin via the interaction of the respective Ca(2+)-binding domains

Sorcin is a penta-EF-hand protein that interacts with intracellular target proteins after Ca(2+) binding. The sarcolemmal Na(+)/Ca(2+) exchanger (NCX1) may be an important sorcin target in cardiac muscle. In this study, RNAi knockdown of sorcin, purified sorcin or sorcin variants was employed in par...

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Detalles Bibliográficos
Autores principales: Zamparelli, Carlotta, Macquaide, Niall, Colotti, Gianni, Verzili, Daniela, Seidler, Tim, Smith, Godfrey L., Chiancone, Emilia
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958309/
https://www.ncbi.nlm.nih.gov/pubmed/20298697
http://dx.doi.org/10.1016/j.yjmcc.2010.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958309/
https://www.ncbi.nlm.nih.gov/pubmed/20298697
http://dx.doi.org/10.1016/j.yjmcc.2010.03.003

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