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MyoD regulates apoptosis of myoblasts through microRNA-mediated down-regulation of Pax3

The molecules that regulate the apoptosis cascade are also involved in differentiation and syncytial fusion in skeletal muscle. MyoD is a myogenic transcription factor that plays essential roles in muscle differentiation. We noticed that MyoD(−/−) myoblasts display remarkable resistance to apoptosis...

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Detalles Bibliográficos
Autores principales: Hirai, Hiroyuki, Verma, Mayank, Watanabe, Shuichi, Tastad, Christopher, Asakura, Yoko, Asakura, Atsushi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958479/
https://www.ncbi.nlm.nih.gov/pubmed/20956382
http://dx.doi.org/10.1083/jcb.201006025