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Release of Mps1 from kinetochores is crucial for timely anaphase onset
Mps1 kinase activity is required for proper chromosome segregation during mitosis through its involvements in microtubule–chromosome attachment error correction and the mitotic checkpoint. Mps1 dynamically exchanges on unattached kinetochores but is largely removed from kinetochores in metaphase. He...
Autores principales: | Jelluma, Nannette, Dansen, Tobias B., Sliedrecht, Tale, Kwiatkowski, Nicholas P., Kops, Geert J.P.L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958484/ https://www.ncbi.nlm.nih.gov/pubmed/20937696 http://dx.doi.org/10.1083/jcb.201003038 |
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