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Ankyrin G restricts ion channel diffusion at the axonal initial segment before the establishment of the diffusion barrier

In mammalian neurons, the precise accumulation of sodium channels at the axonal initial segment (AIS) ensures action potential initiation. This accumulation precedes the immobilization of membrane proteins and lipids by a diffusion barrier at the AIS. Using single-particle tracking, we measured the...

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Detalles Bibliográficos
Autores principales: Brachet, Anna, Leterrier, Christophe, Irondelle, Marie, Fache, Marie-Pierre, Racine, Victor, Sibarita, Jean-Baptiste, Choquet, Daniel, Dargent, Bénédicte
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958486/
https://www.ncbi.nlm.nih.gov/pubmed/20956383
http://dx.doi.org/10.1083/jcb.201003042