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Ankyrin G restricts ion channel diffusion at the axonal initial segment before the establishment of the diffusion barrier
In mammalian neurons, the precise accumulation of sodium channels at the axonal initial segment (AIS) ensures action potential initiation. This accumulation precedes the immobilization of membrane proteins and lipids by a diffusion barrier at the AIS. Using single-particle tracking, we measured the...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958486/ https://www.ncbi.nlm.nih.gov/pubmed/20956383 http://dx.doi.org/10.1083/jcb.201003042 |