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The Physiological Period Length of the Human Circadian Clock In Vivo Is Directly Proportional to Period in Human Fibroblasts

BACKGROUND: Diurnal behavior in humans is governed by the period length of a circadian clock in the suprachiasmatic nuclei of the brain hypothalamus. Nevertheless, the cell-intrinsic mechanism of this clock is present in most cells of the body. We have shown previously that for individuals of extrem...

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Detalles Bibliográficos
Autores principales: Pagani, Lucia, Semenova, Ekaterina A., Moriggi, Ermanno, Revell, Victoria L., Hack, Lisa M., Lockley, Steven W., Arendt, Josephine, Skene, Debra J., Meier, Fides, Izakovic, Jan, Wirz-Justice, Anna, Cajochen, Christian, Sergeeva, Oksana J., Cheresiz, Sergei V., Danilenko, Konstantin V., Eckert, Anne, Brown, Steven A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958564/
https://www.ncbi.nlm.nih.gov/pubmed/21042402
http://dx.doi.org/10.1371/journal.pone.0013376