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Differential Contribution to Neuroendocrine Tumorigenesis of Parallel Egfr Signaling in Cancer Cells and Pericytes

Factors associated with tumor sensitivity to epidermal growth factor receptor (EGFR) inhibitors in the context of wild-type EGFR remain elusive. This study investigates the mechanistic basis of responsiveness to EGFR inhibitors in the RIP1-Tag2 (RT2) mouse model of pancreatic neuroendocrine tumorige...

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Detalles Bibliográficos
Autores principales: Nolan-Stevaux, Olivier, Truitt, Morgan C., Pahler, Jessica C., Olson, Peter, Guinto, Cristina, Lee, David C., Hanahan, Douglas
Formato: Texto
Lenguaje:English
Publicado: SAGE Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958675/
https://www.ncbi.nlm.nih.gov/pubmed/20975924
http://dx.doi.org/10.1177/1947601909358722