Cargando…
Differential Contribution to Neuroendocrine Tumorigenesis of Parallel Egfr Signaling in Cancer Cells and Pericytes
Factors associated with tumor sensitivity to epidermal growth factor receptor (EGFR) inhibitors in the context of wild-type EGFR remain elusive. This study investigates the mechanistic basis of responsiveness to EGFR inhibitors in the RIP1-Tag2 (RT2) mouse model of pancreatic neuroendocrine tumorige...
Autores principales: | Nolan-Stevaux, Olivier, Truitt, Morgan C., Pahler, Jessica C., Olson, Peter, Guinto, Cristina, Lee, David C., Hanahan, Douglas |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958675/ https://www.ncbi.nlm.nih.gov/pubmed/20975924 http://dx.doi.org/10.1177/1947601909358722 |
Ejemplares similares
-
Functions of Paracrine PDGF Signaling in the Proangiogenic Tumor Stroma Revealed by Pharmacological Targeting
por: Pietras, Kristian, et al.
Publicado: (2008) -
Identification and Characterization of Poorly Differentiated Invasive Carcinomas in a Mouse Model of Pancreatic Neuroendocrine Tumorigenesis
por: Hunter, Karen E., et al.
Publicado: (2013) -
Deficiency for the Cysteine Protease Cathepsin L Impairs Myc-Induced Tumorigenesis in a Mouse Model of Pancreatic Neuroendocrine Cancer
por: Brindle, Nicola R., et al.
Publicado: (2015) -
A set of microRNAs coordinately controls tumorigenesis, invasion, and metastasis
por: Michael, Iacovos P., et al.
Publicado: (2019) -
EBF1 is expressed in pericytes and contributes to pericyte cell commitment
por: Pagani, Francesca, et al.
Publicado: (2021)