Genetic Variations in Human Glutathione Transferase Enzymes: Significance for Pharmacology and Toxicology

Glutathione transferase enzymes (GSTs) catalyze reactions in which electrophiles are conjugated to the tripeptide thiol glutathione. While many GST-catalyzed transformations result in the detoxication of xenobiotics, a few substrates, such as dihaloalkanes, undergo bioactivation to reactive intermed...

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Detalles Bibliográficos
Autor principal: Josephy, P. David
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958679/
https://www.ncbi.nlm.nih.gov/pubmed/20981235
http://dx.doi.org/10.4061/2010/876940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958679/
https://www.ncbi.nlm.nih.gov/pubmed/20981235
http://dx.doi.org/10.4061/2010/876940

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