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Genetic Variations in Human Glutathione Transferase Enzymes: Significance for Pharmacology and Toxicology
Glutathione transferase enzymes (GSTs) catalyze reactions in which electrophiles are conjugated to the tripeptide thiol glutathione. While many GST-catalyzed transformations result in the detoxication of xenobiotics, a few substrates, such as dihaloalkanes, undergo bioactivation to reactive intermed...
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| Formato: | Texto |
| Lenguaje: | English |
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SAGE-Hindawi Access to Research
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958679/ https://www.ncbi.nlm.nih.gov/pubmed/20981235 http://dx.doi.org/10.4061/2010/876940 |