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Functional Interchangeability of Late Domains, Late Domain Cofactors and Ubiquitin in Viral Budding

The membrane scission event that separates nascent enveloped virions from host cell membranes often requires the ESCRT pathway, which can be engaged through the action of peptide motifs, termed late (L-) domains, in viral proteins. Viral PTAP and YPDL-like L-domains bind directly to the ESCRT-I and...

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Detalles Bibliográficos
Autores principales: Zhadina, Maria, Bieniasz, Paul D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958808/
https://www.ncbi.nlm.nih.gov/pubmed/20975941
http://dx.doi.org/10.1371/journal.ppat.1001153