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Loss of the p53/p63 Regulated Desmosomal Protein Perp Promotes Tumorigenesis

Dysregulated cell–cell adhesion plays a critical role in epithelial cancer development. Studies of human and mouse cancers have indicated that loss of adhesion complexes known as adherens junctions contributes to tumor progression and metastasis. In contrast, little is known regarding the role of th...

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Detalles Bibliográficos
Autores principales: Beaudry, Veronica G., Jiang, Dadi, Dusek, Rachel L., Park, Eunice J., Knezevich, Stevan, Ridd, Katie, Vogel, Hannes, Bastian, Boris C., Attardi, Laura D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958815/
https://www.ncbi.nlm.nih.gov/pubmed/20975948
http://dx.doi.org/10.1371/journal.pgen.1001168