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Loss of the p53/p63 Regulated Desmosomal Protein Perp Promotes Tumorigenesis
Dysregulated cell–cell adhesion plays a critical role in epithelial cancer development. Studies of human and mouse cancers have indicated that loss of adhesion complexes known as adherens junctions contributes to tumor progression and metastasis. In contrast, little is known regarding the role of th...
Autores principales: | Beaudry, Veronica G., Jiang, Dadi, Dusek, Rachel L., Park, Eunice J., Knezevich, Stevan, Ridd, Katie, Vogel, Hannes, Bastian, Boris C., Attardi, Laura D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958815/ https://www.ncbi.nlm.nih.gov/pubmed/20975948 http://dx.doi.org/10.1371/journal.pgen.1001168 |
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