The PTPN22 Locus and Rheumatoid Arthritis: No Evidence for an Effect on Risk Independent of Arg620Trp

OBJECTIVES: The Trp(620) allotype of PTPN22 confers susceptibility to rheumatoid arthritis (RA) and certain other classical autoimmune diseases. There has been a report of other variants within the PTPN22 locus that alter risk of RA; protective haplotype ‘5’, haplotype group ‘6–10’ and susceptibilit...

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Detalles Bibliográficos
Autores principales: Wan Taib, Wan R., Smyth, Deborah J., Merriman, Marilyn E., Dalbeth, Nicola, Gow, Peter J., Harrison, Andrew A., Highton, John, Jones, Peter B. B., Stamp, Lisa, Steer, Sophia, Todd, John A., Merriman, Tony R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958827/
https://www.ncbi.nlm.nih.gov/pubmed/20975833
http://dx.doi.org/10.1371/journal.pone.0013544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958827/
https://www.ncbi.nlm.nih.gov/pubmed/20975833
http://dx.doi.org/10.1371/journal.pone.0013544

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