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Nutritional Programming in the Rat Is Linked to Long-Lasting Changes in Nutrient Sensing and Energy Homeostasis in the Hypothalamus

BACKGROUND: Nutrient deficiency during perinatal development is associated with an increased risk to develop obesity, diabetes and hypertension in the adulthood. However, the molecular mechanisms underlying the developmental programming of the metabolic syndrome remain largely unknown. METHODOLOGY/P...

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Detalles Bibliográficos
Autores principales: Orozco-Solís, Ricardo, Matos, Rhowena J. B., Guzmán-Quevedo, Omar, Lopes de Souza, Sandra, Bihouée, Audrey, Houlgatte, Rémi, Manhães de Castro, Raul, Bolaños-Jiménez, Francisco
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958833/
https://www.ncbi.nlm.nih.gov/pubmed/20975839
http://dx.doi.org/10.1371/journal.pone.0013537