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Activated mammalian target of rapamycin is a potential therapeutic target in gastric cancer

BACKGROUND: The mammalian target of rapamycin (mTOR) plays a key role in cellular growth and homeostasis. The purpose of our present study is to investigate the expression of activated mTOR (p-mTOR) in gastric cancer patients, their prognostic significance and the inhibition effect of RAD001 on tumo...

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Detalles Bibliográficos
Autores principales: Xu, Da-zhi, Geng, Qi-rong, Tian, Ying, Cai, Mu-yan, Fang, Xin-juan, Zhan, You-qing, Zhou, Zhi-wei, Li, Wei, Chen, Ying-bo, Sun, Xiao-wei, Guan, Yuan-xiang, Li , Yuan-fang, Lin, Tong-yu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958947/
https://www.ncbi.nlm.nih.gov/pubmed/20929525
http://dx.doi.org/10.1186/1471-2407-10-536